Human Sera
Cayman Chemical ClenbuterolhydrochlorIde 50mg
A β2-AR agonist; induces relaxation of equine tracheal muscle strips (EC50 = 2.1 nM); increases the number of autophagosomes and autophagic flux in HepG2 cells at 300 nM; increases blood flow to adipose tissue and induces weight gain in rats at 2 mg/kg; induces relaxation of bovine uterus; inhibits infection of MDCK cells by an H1N1 influenza isolate in vitro (EC50 = 9.4 µM)
Cayman Chemical IsoxnthopterIn 50mg
A natural intermediate in the pteridine pathway that can be produced naturally from 7-oxobiopterin or in vitro by the oxidation of pterin by xanthine oxidase
Cayman Chemical UmIfenovIrhydrochlorIde 100mg
A broad-spectrum antiviral agent; inhibits the replication of H5N1 influenza (IC50 = 30 UG/ml) and SARS-CoV-2 in vitro (IC50 = 3.537 µM); inhibits entry of HCV pseudoparticles in Huh7 cells (IC50 = 6 UG/ml); reduces the formation of influenza-induced lung lesions in ferrets at 45 mg/kg
Cayman Chemical ProcarbazInhydrochlorIde 50mg
A methyl hydrazine derivative that is converted by metabolism into a methylating species which converts DNA to various DNA adducts, including O6-methylguanine
Cayman Chemical Cholesterolplnt 100mg
A minor plant sterol; a precursor in the synthesis of various bioactive plant metabolites
Cayman Chemical MoexIprIlhydrochlorIde 100mg
A prodrug form of moexiprilat; inhibits ACE in a cell-free assay (IC50 = 2.7 µM); Inhibits PDE4 (IC50s = 38, 160, and 230 µM for PDE4B2, PDE4A5, and PDE4D5, respectively); reduces blood pressure in spontaneously hypertensive rats at 0.1-30 mg/kg per day; reduces infarct volume in a rat model of focal cerebral ischemia at 0.1 mg/kg
Cayman Chemical DegarelIxacetate 50mg
A synthetic GNRHR antagonist (IC50 = 3 nM in HEK293 cells expressing the human receptor); inhibits the growth of WPMY-1, WPE1-NA22, BPH-1, and LNCaP prostate cell lines via caspase activation and induction of apoptosis (10 μM); decreases plasma testosterone levels in rats to castrate levels for the first 49 days post treatment (2 mg/kg); decreases tumor volume of Dunning R3327H prostate tumor flank implants in rats (1 mg/kg per month)
Cayman Chemical VIlazodonhydrochlorIde 50mg
An SSRI and a partial agonist of 5-HT1A (IC50 s = 0.2 and 0.5 nM, respectively); increases extracellular 5-HT in the rat ventral hippocampus and frontal cortex at 1 and 3 mg/kg, i.p.; decreases immobility in the forced swim test in both rats and mice at 1 mg/kg
Cayman Chemical SematIlIdehydrochlorIde 50mg
A class III antiarrhythmic agent; prolongs electrically stimulated APD and increases ERP in isolated guinea pig left atria; decreases spontaneous sinoatrial beating rates and induces ERP prolongation of the atrioventricular node in isolated perfused canine hearts; increases ERP, prolonging cardiac refractoriness, in situ in open-chest dog hearts at 1 mg/kg; inhibits PES-induced arrhythmias in dogs
Cayman Chemical MozavaptnhydrochlorIde 50mg
A vasopressin V2 receptor antagonist (Ki = 9.42 nM in HeLa cells expressing the human receptor); selective for vasopressin V2 over V1 receptors (IC50s = 14 and 1,200 nM, respectively) in radioligand binding assays using rat kidney and rat liver membranes, respectively; increases urine volume and decreases urine osmolality in rats from 10-30 mg/kg
Cayman Chemical 1PalmItoyl2ArachIdonylsn 100mg
A phospholipid; found in biological membranes; is oxidized in vivo and has been used to study signaling of oxidized phospholipids; levels are decreased in isolated human multiple myeloma cells
Cayman Chemical UDPNacetylDGlucosamIns 50mg
A nucleotide sugar that is used by glycosyltransferases to transfer N-acetylglucosamine residues to substrates